SAMe 400 mg (60 Tabs)
Brand: Jarrow
Product UPC: 790011200420
Item: J20042
Suggested Retail Price*
$81.99
Our Price
$61.49
(25% Below Retail)
-
+
Buy Now!

Jarrow Formulas® SAMe 400 provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

With More of the Biologically Active S,S than R,S Form Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made naturally by microbiological fermentation and processed without chemical solvents to preserve 68-80% (S,S) SAMe.

SAMe supports:

Brain Metabolism and Mood*
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes.* It has also been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood.*

Joint Health*
SAMe supports the production of healthy connective tissue through transsulfuration.* In this transsulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.*

Liver Function*
SAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.*

Directions: Adults take 1 tablet once a day on an empty stomach or as directed by your qualified healthcare professional.

Ingredients: 1 Tablet supplies:
S-Adenosyl Methionine (from 800 mg of SAMe Tosylate Disulfate) 400 mg

Other Ingredients: Microcrystalline cellulose, coating (hypromellose acetate succinate, stearic acid [vegetable source], triethyl citrate and riboflavin), glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol and sodium starch glycolate.

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.

EnterzoGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

Warning: Do not use if pregnant or nursing. Individuals with Parkinson’s disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use.
KEEP OUT OF THE REACH OF CHILDREN. STORE IN A COOL, DRY PLACE.

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

Best Way to Use SAMe 400 mg for Maximum Benefits

  1. Consult with a healthcare provider: Before starting any new supplement regimen, it is important to consult with a healthcare provider to ensure it is safe and appropriate for your individual health needs.
  2. Follow recommended dosage: The recommended dosage of SAMe 400 mg can vary depending on the individual and the reason for taking it. It is important to follow the dosage instructions provided on the product packaging or as advised by a healthcare provider.
  3. Take on an empty stomach: SAMe is best absorbed on an empty stomach, typically 30 minutes to an hour before a meal. This can help maximize its effectiveness.
  4. Consistency is key: For SAMe to be most effective, it is important to take it consistently as directed. Skipping doses or inconsistent use may impact its benefits.
  5. Monitor for side effects: While SAMe is generally considered safe for most people, some individuals may experience side effects such as nausea, dry mouth, or headache. If you experience any adverse reactions, discontinue use and consult with a healthcare provider.
  6. Consider time of day: Some individuals find it beneficial to take SAMe in the morning to help boost energy levels and mood throughout the day. However, others may prefer taking it in the evening to help promote relaxation and improve sleep quality.

SAMe is a natural compound that may offer a variety of potential health benefits, including support for joint health, mood regulation, and liver function. By following these tips for using SAMe 400 mg, you can help maximize its benefits and support your overall well-being.

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

SAMe 400 mg Ingredients:

  • S-Adenosyl-L-Methionine (from 800 mg of SAMe disulfate tosylate)
  • Other Ingredients: Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium stearate, triethyl citrate, titanium dioxide, magnesium silicate, titanium dioxide, magnesium silicate, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch, and iron oxide red

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

Alternative to SAMe 400 mg

When looking for an alternative to SAMe 400 mg, one option to consider is Methylfolate. Methylfolate is the active form of vitamin B9, also known as folic acid. It plays a crucial role in supporting mental health and overall well-being.

Benefits of Methylfolate:

  • Supports mental health
  • Helps in the production of neurotransmitters
  • Aids in the synthesis of DNA and RNA
  • Supports cardiovascular health

Recommended Dosage:

It is recommended to consult with a healthcare provider to determine the appropriate dosage of Methylfolate based on individual needs and health conditions.

Sources:

For more information on Methylfolate and its benefits, you can visit the website of Thorne, a reputable maker of nutritional supplements.

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

Health Benefits of SAMe 400 mg

  1. Supports Joint Health

    SAMe (S-adenosylmethionine) has been shown to help support joint health by reducing inflammation and promoting the production of proteoglycans, which are important for joint lubrication and cushioning.

  2. Improves Mood and Mental Health

    SAMe is involved in the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which play a crucial role in regulating mood. Taking SAMe supplements may help improve mood and alleviate symptoms of depression.

  3. Liver Support

    SAMe is essential for the synthesis of glutathione, a powerful antioxidant that helps protect liver cells from damage. Taking SAMe supplements may help support liver function and detoxification.

  4. Supports Cognitive Function

    Some studies suggest that SAMe may have a positive impact on cognitive function and may help improve memory and focus, although more research is needed in this area.

  5. May Help with Fibromyalgia Symptoms

    Some research indicates that SAMe may help reduce pain, stiffness, and fatigue associated with fibromyalgia, a chronic pain condition. However, more studies are needed to confirm these benefits.

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

SAMe 400 mg Comparison

When comparing SAMe 400 mg with similar products, it is important to consider the quality, dosage, and potential benefits. SAMe, which stands for S-adenosyl-L-methionine, is a compound that is naturally produced in the body and plays a role in various biochemical processes.

Quality:

SAMe 400 mg is a common dosage of SAMe supplements available in the market. It is important to choose a reputable brand that uses high-quality ingredients and follows good manufacturing practices to ensure the purity and effectiveness of the product.

Dosage:

The dosage of SAMe can vary depending on the individual's needs and health condition. A dosage of 400 mg is considered to be a moderate level and may be suitable for general support of mood and joint health. However, it is always recommended to consult with a healthcare provider to determine the appropriate dosage for your specific needs.

Potential Benefits:

SAMe is believed to have potential benefits for mood support, joint health, and liver function. Research suggests that SAMe may help with symptoms of depression, osteoarthritis, and liver conditions. However, more studies are needed to fully understand the effectiveness of SAMe for these conditions.

It is important to note that individual responses to supplements may vary, and it is always best to consult with a healthcare provider before starting any new supplement regimen.

For more information on SAMe 400 mg and its comparison with similar products, it is recommended to refer to the official website of the manufacturer or consult with a healthcare professional.

The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.

©1996-2026 BetterLife.com, Inc. All rights reserved, Designated trademarks and brands are the property of their respective owners. The products and the claims made about specific products on or through this site have not been evaluated by betterLife.com Inc. or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should NOT use the information on this site for diagnosis or treatment of any health problems or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

*Definition of Price related terms:

The Terms "Suggested Retail Price" or "Retail Price" denote the Manufacturer's Suggested Retail Price. The product may be sold by vendors at a different price. The Terms "Savings" or "Your Savings" refer to the difference between the "Suggested Retail Price" and the price being offered by betterlife.com Inc. The Term "Below Retail" refers to the difference between the "Suggested Retail Price" and the price being offered by betterlife.com Inc.

Prices and promotions are subject to change without notice.