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Life Extension® first introduced SAMe (S-Adenosyl-Methionine) in 1997, and researchers continue to discover impressive benefits of this versatile nutrient.
SAMe is an amino acid derivative normally synthesized in the body that may become depleted with sickness or age. Supplementing with SAMe plus folate, trimethylglycine (TMG or betaine), vitamins B6 and B12 appears to be an effective way to overcome this deficiency.
SAMe is concentrated in the liver and brain and is a major methyl donor in the synthesis of hormones, nucleic acids, proteins, and phospholipids, and catecholamines and other neurotransmitters. SAMe is required for the synthesis of norepinephrine, dopamine, and serotonin.SAMe facilitates glutathione4, usage, which improves the body's antioxidant defense. It also helps maintain acetylcholine levels6, which are necessary for cognitive function.
Warning: SAMe should not be taken by those diagnosed with bipolar disorder. KEEP OUT OF REACH OF CHILDREN DO NOT EXCEED RECOMMENDED DOSE Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
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