The biological functions of vitamin B6 (pyridoxine) are accomplished by its coenzyme form, pyridoxal-5-phosphate. Pyridoxal-5-phosphate’s actions mainly involve the metabolism of amino acids and other nitrogen compounds. In the liver, pyridoxal-5-phosphate is essential for glucose production from amino acids through its role as a coenzyme for the transaminase enzymes.
Pyridoxal-5-phosphate is also needed in the liver and muscles to access stored glycogen for glucose production, and to synthesize niacin from the amino acid tryptophan. In red blood cells, pyridoxal-5-phosphate is needed for hemoglobin synthesis, and regulation of oxygen affinity. Moreover, cell receptivity to steroid hormones is influenced by pyridoxal-5-phosphate.
In the nervous system, pyridoxal-5-phosphate is needed for synthesis of several neurotransmitters, including serotonin (from tryptophan), taurine, dopamine, norepinephrine, histamine, and gammaaminobutyric acid (GABA). Many experimental and clinical observations support the fact that dietary vitamin B6 is required to maintain normal nervous system function. Along with vitamin B12 and folic acid, pyridoxal-5-phosphate is involved in single carbon metabolism, and is necessary for maintaining normal plasma homocysteine levels. Elevated plasma homocysteine may be an independent risk factor for the development of cardiovascular disease. Also, due to its involvement in single carbon metabolism, pyridoxal-5-phosphate assists in maintaining normal immune function.
Directions: One capsule daily, or as directed by physician.
Ingredients: 1 capsule supplies:
Pyridoxal-5-Phosphate...................................50 mg
The information provided is for educational purposes only and is not intended to replace professional medical advice. Always consult with a qualified healthcare provider for personalized medical guidance.
